Why the first day of a trip isn't the time for a long drive.
Sleep deprivation affects reaction time in ways similar to alcohol impairment, even when you don't feel obviously tired. Long-haul flights across multiple time zones compound this, since your body clock is fighting the local schedule on top of general travel fatigue.
If possible, build a buffer day into your itinerary before a long drive, rather than picking up a rental car straight from the airport. Short, frequent breaks help more than pushing through a long stretch on minimal sleep.